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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPRD1B All Species: 27.88
Human Site: T149 Identified Species: 47.18
UniProt: Q9NQG5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQG5 NP_067038.1 326 36900 T149 E K K S L K R T F Q Q I Q E E
Chimpanzee Pan troglodytes XP_001143572 314 35607 T139 Q K K S L K R T F Q Q I Q E E
Rhesus Macaque Macaca mulatta XP_001090633 314 35593 T139 D K K S L K R T F Q Q I Q E E
Dog Lupus familis XP_542990 477 52007 T300 E K K S L K R T F Q Q I Q E E
Cat Felis silvestris
Mouse Mus musculus Q9CSU0 326 36865 T149 E K K S L K R T F Q Q I Q E E
Rat Rattus norvegicus NP_001092197 326 36865 T149 E K K S L K R T F Q Q I Q E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512622 400 45577 V227 E K K S R K R V Y E Q I K V D
Chicken Gallus gallus Q5ZM30 268 30818 E98 H V S S E S D E S C K K H P G
Frog Xenopus laevis NP_001086593 325 36801 R148 N E E K S L K R T F Q Q I Q E
Zebra Danio Brachydanio rerio NP_955850 335 38090 V158 L K R S Y Q K V Q E E E E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396379 332 37569 S155 I E K E R K K S E T E V E V D
Nematode Worm Caenorhab. elegans P34281 315 36355 F140 Q V K L S G S F P T P A V A N
Sea Urchin Strong. purpuratus XP_779930 352 40189 T174 E E E S T P A T K K P K L E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05543 409 46470 A140 T E S S P V E A L V L P Q K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 95.4 68.3 N.A. 99.3 99.3 N.A. 53.7 54.5 84.3 79.4 N.A. N.A. 54.8 24.5 50.2
Protein Similarity: 100 95.4 96.3 68.3 N.A. 99.6 99.6 N.A. 65.2 70.5 92.6 90.4 N.A. N.A. 71.6 46.6 68.4
P-Site Identity: 100 93.3 93.3 100 N.A. 100 100 N.A. 53.3 6.6 13.3 26.6 N.A. N.A. 13.3 6.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 13.3 40 66.6 N.A. N.A. 60 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 22 % D
% Glu: 43 29 15 8 8 0 8 8 8 15 15 8 15 58 58 % E
% Phe: 0 0 0 0 0 0 0 8 43 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 50 8 0 0 % I
% Lys: 0 58 65 8 0 58 22 0 8 8 8 15 8 8 0 % K
% Leu: 8 0 0 8 43 8 0 0 8 0 8 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 8 8 0 0 8 0 15 8 0 8 0 % P
% Gln: 15 0 0 0 0 8 0 0 8 43 58 8 50 8 0 % Q
% Arg: 0 0 8 0 15 0 50 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 15 79 15 8 8 8 8 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 8 0 0 50 8 15 0 0 0 0 0 % T
% Val: 0 15 0 0 0 8 0 15 0 8 0 8 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _